Intensive chemotherapy and recombinant human G-CSF in later chronic-phase-accelerated-phase chronic myeloid leukaemia

Multicentre centrally randomised, comparative study of the efficacy and safety of cefpirome (HR810) plus gentamicin versus piperacillin plus gentamicin in the initial management of febrile neutropenic patients

Postoperative adjuvant radiotherapy in the treatment of patients with cutaneous melanoma of the head and neck

Bone marrow transplantation in aplastic anaemia

Gencitabine in patients with advanced epithelial ovarian cancer

Multicentre trial of tamoxifen to prevent breast cancer

Phase III prospective randomised clinical trial of accelerated radiotherapy (ART) for stage III and stage IV squamous carcinoma of the upper aerodigestive tract

Peptide T: an evaluation of its effect on the nutrional status and quality of life of patients with advanced cancer

Phase II intergroup prospectively randomised trial of perioperative 5-fluorouracil after curative resection, followed by 5-fluorouracil and levamisole for patients with colon cancer

Phase II prospective study of postoperative accelerated radiotherapy for high risk squamous carcinoma of the upper aerodigestive tract

Trial of early autologous bone marrow transplant in intermediate grade non-Hodgkins lymphoma

Adjuvant tamoxifen: longer against shorter

Phase II study of synchronous carboplatin-etoposide and radiation in merkel cell carcinoma of the skin

Phase II trial of high-dose epirubicin combined with ifosfamide and mesna, followed by filgrastim (G-CSF) support in patients with advanced soft tissue sarcomas

Phase II trial of evaluating efficacy of administering procarbazine prior to BCNU combined with vincristine in relapsed high grade gliomas

Assessment of parameters of response to combined modality treatment of locally advanced breast cancer

Phase III randomised study to evaluate the effects of two conventionally fractionated radiation regimens for early prostate carcinoma on anorectal function and survival

Fluorouracil-leucovorin with preoperative irradiation vs radiotherapy alone, and postoperative 5-fluorouracil-cyclophosphamide vs no adjuvant therapy in patients with resectable T3/4 adenocarcinoma of the rectum

Prospective randomised multicentre phase III clinical trial comparing the effects of panorex injection plus 5-fluorouracil-leucovorin vs 5-fluorouracil-leucovorin vs panorex injection alone in patients with surgically resected stage III (Dukes C) carcinoma of the colon

International field study of the reliability and validity of the EORTC QLQ-C30 (version 3.0) and a disease-specific questionnaire module (the QLQ-BR23) in assessing the quality of life of patients with breast cancer

Randomised double-blind in postmenopausal women with primary breast cancer who have received adjuvant tamoxifen for 2-3 years, comparing subsequent adjuvant exemestane treatment with further tamoxifen

Hormonal replacement therapy after breast cancer diagnosis: is it safe?

Chemotherapy both before and after local treatment versus chemotherapy only after local treatment for women with locally advanced breast cancer

Randomised phase III study of chemotherapy and radiotherapy vs radiotherapy alone as adjuvant treatment to patients with node positive stages IB and IIA cervix cancer

Immunisation and testing of adenocarcinoma patients using intramuscular mannan-muci fusion protein (MFP) and low dose cyclophosphamide

Phase II study of taxotere and carboplatin combination chemotherapy in unresectable metastatic and locally advanced non-small cell lung cancer

Cancer patients' education and role modelling for clinical decisions

Brain metastases radiation fractionation: a prospective randomised study

Randomised comparison of breast conservation with or without lumpectomy radiotherapy boost

International phase III trial of primary therapy for B-cell chronic lymphocytic leukaemia

MMT 95 study for rhabdomyosarcoma and other malignant soft tissue tumours of childhood

Immunisation of patients with adenocarcinoma using subcutaneous mannan-muci fusion protein and recombinant human IL-12 (not available)

Chimeric anti-CD20 monoclonal antibody in remission induction and maintenance treatment of relapsed follicular non-Hodgkin's lymphoma: a phase III randomised clinical trial

Intergroup phase III trial to evaluate the activity of docetaxel, given either sequentially or in combination with doxorubicin, followed by CMF, in comparison to doxorubicin alone or in combination with cyclophosphamide, by CMF, in the treatment of node-positive breast cancer patients (IBCSG 20-98, BIG 2-98)

Phase I pilot study of intensive chemotherapy with peripheral blood stem cell rescue in infants with malignant brain or spinal cord tumours

Phase I study of monoclonal antibody F19 (BIBH-1) in patients with unresectable, advanced or metastatic fibroblast activation protein-positive colorectal cancer

Phase I/II study of concurrent carboplatin, vincristine, and radiotherapy followed by adjuvant chemotherapy in children with newly diagnosed high risk primitive neuroectodermal tumour

Phase II pilot study of an intensified modification of the New York I regimen for untreated disseminated pediatric anaplastic (Ki-1 positive) large cell and large T-cell lymphoma: addition of VP-16 and ARA-C, increase in MTX dose, and use of PEG-ASP

Phase II pilot study of intensified induction/consolidation followed by intensified re-induction/re-intensification in infants less than 1 years of age with newly diagnosed acute lymphoblastic leukaemia

Phase II pilot study of peripheral blood stem cell transplantation after preparative therapy consisting of cyclophosphamide, carmustine, and etoposide for recurrent and primarily refractory hodgkin's and non-hodgkin's childhood lymphoma

Phase II study of docetaxel in children with recurrent solid tumours

Phase II study of donor leukocyte infusions in patients with recurrent or persistent hematologic malignancies after allogeneic bone marrow transplantation

Phase II study of oral topotecan in children with relapsed acute lymphocytic leukaemia, acute myeloid leukaemia, or blastic phase chronic myelogenous leukaemia

Phase II study of salvage chemotherapy for acute myeloid leukaemia or myelodysplastic syndrome in first relapse or refractory to initial remission induction therapy and for secondary acute myeloid leukaemia

Phase II study of topotecan in children with recurrent or refractory brain tumours, sarcomas or neuroblastomas

Phase II study of vinorelbine in children with recurrent or refractory malignancies

Phase II upfront window study of irinitecan follwed by multimodal, multiagent therapy in selected children and adolescents with newly diagnosed stage IV clinical group IV rhabdomyosarcoma

Phase III multimodality therapy based on histology, stage, age, and tumour size in children with Wilm's tumour, clear cell sarcoma of the kidney, and rhabdoid tumours of the kidney

Phase III mutimodality therapy based on prior treatment and histology for patients with relapsed wilm's tumour, clear cell sarcoma of the kidney, and rhabdoid tumours of the kidney

Phase III nonrandomised study of primary surgical therapy in children with low risk neuroblastoma

Phase III pilot study of three intensification regimens and phase III randomised study of intensification therapy plus dexrazoxane in patients with newly diagnosed, nonmetastatic osteosarcoma

Phase III randomised international study of reduction in intensification of the LMB 89 regimen for non-hodgkin's lymphoma: reduced doses of CTX for intermediate risk patients and less maintenance therapy for intermediate risk and high risk patients

Phase III randomized study of immunotherapy with polyvalent melanoma vaccine (CancerVax) plus BCG versus BCG plus placebo following surgery in patients with stage IV melanoma

Phase I study of arsenic trioxide in pediatric patients with refractory leukaemia or lymphoma

Phase I study of fenretinide in children with high risk solid tumors

Phase I study of gadolinium texaphyrin and radiotherapy in children with newly diagnosed diffuse intrinsic pontine glioma

Phase I study of gemcitabine in pediatric patients with refractory solid tumors

Phase I study of monoclonal antibody Ch14.18 with sargramostim (GM-CSF) immediatley following autologous marrow or PBSC transplantation and interleukin-2 (IL-2) in children with neuroblastoma

Phase I study of PSC-833 in combination with etoposide and mitoxantrone for refractory or relapsed pediatric acute leukaemia

Phase I study of recombinant human thrombopoietin with filgrastim (G-CSF) in children receiving ifosfamide, carboplatin, and etoposide chemotherapy for recurrent or refractory solid tumours

Phase II pilot study of bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone, filgrastim (G-CSF), dacarbazine, vinblastine, and radiotherapy in pediatric patients with previously untreated stage II, III or IV Hodgkin's

Phase II study of intensified alternating regimens of VAdrC (vincristine, doxorubicin, cyclophosphamide) and IE (ifosfamide, etoposide) in newly diagnosed, metastatic Ewing 's sarcoma and primitve neuroectodermal tumour

Phase II study of irinotecan in children with refractory CNS or solid tumors

Phase III randomized study of adjuvant lomustine/cisplatin/vincristine vs cyclophosphamide/cisplatin/vincristine following craniospinal radiotherapy in children with newly diagnosd, average-risk medulloblastoma

Phase III randomized study of BCG plus a polyvalent melanoma vaccine (CancerVax) versus BCG plus placebo in patients with resected stage III melanoma

Phase III randomized study of high dose versus standard dose prophylactic cranial radiotherapy in patients with limited stage small cell lung cancer in complete remission

Phase III randomized study of interleukin-2 plus histamine dihydrochloride (maxamine) versus no further therapy (standard of care) in patients with acute myeloid leukemia in first or subsequent complete remission following consolidation therapy

Phase III randomized study of postoperative cisplatin, vincristine, and flourouracil with or without amifostine versus carboplatin and cisplatin with or without amifostine in children with hepatoblastoma

Phase III randomized study of response-dependent therapy with doxorubicin/bleomycin/vincristine/etoposide (DBVE) with vs without dexrazoxane followed by low-dose involved-field radiotherapy for newly diagnosed stage IA, IIA, IIIA1 childhood Hodgkin's disease

Phase III randomized study of rituximab in patients with relapsed follicular non-Hodgkin's lymphoma

Phase III randomized study of standard anitbiotic therapy with or without filgrastim in children with chemotherapy induced febrile neutropenia

Phase III randomized study of surgery with or without axillary node clearance followed by adjuvant tamoxifen in elderly women with breast cancer

Phase III randomized study of the efficacy, safety, and toleration of voriconazole vs amphotericin B in the treatment of acute invasive aspergillosis in immunocompromised patients

Phase III randomized study of treatment based on response to induction chemotherapy in patients with higher risk childhood acute lymphocytic leukemia: standard vs augmented Berlin-Frankfurt-Munster regimen with standard vs prolonged intensification for ra

Phase III study of carboplatin and vincristine vs thioguanine, procarbazine, lomustine (CCNU), and vincristine for progressive low grade astrocytoma in children less than 10 years old

Phase III study of children with down syndrome and transient myeloproliferative disorder, acute myelogenous leukemia, or myelodysplastic syndrome

Phase III study of combination chemotherapy in children with intermediate risk neuroblastoma

Phase III study of dactinomycin and vincristine with or without cyclophosphamide and/or radiation therapy in patients with newly diagnosed low risk rhabdomyosarcoma of embryonal or botyroid subtype

Phase III study of systemic chemotherapy combined with local therapy for isolated extramedullary relapse of acute lymphoblastic leukemia

Detection of minimal residual disease in children receiving therapy for acute myeloid leukemia or myelodysplastic syndrome

Diagnostic study of p16/p15 gene alterations in children with relapsed acute lymphocytic leukemia treated on protocol CCG-1941

Molecular biology of pediatric brain tumors

Study of molecular genetic lesions and clinical outcomes in children with acute lymphoblastic leukemia

Phase II study examining the efficacy of short fractionation radiotherapy for the palliation of liver metastases

A randomised trial of whole brain irradiation following local treatment of solitary brain metastases

Concurrent radiotherapy and chemotherapy for oesophageal cancer patients

ANZLG/TROG prospective study of limited chemotherapy and involved field radiotherapy for patients with clinical stage I-II Hodgkin's disease

Randomised multicentre trial of involved field radiotherapy versus involved field radiotherapy plus chemotherapy for stage I-II low grade follicular lymphoma

Prospective, non-randomised study of chemotherapy and radiotherapy for osteolymphoma (OL)

Tumour volume as an independent prognostic factor in patients with non-small cell lung cancer: A protocol for a prospective database

Phase II study of intrathecal topotecan in pediatric patients with refractory meningeal malignancy

Phase II study of vinblastine and methotrexate in children with desmoid tumors that are recurrent or untreatable with surgery or irradiation

Phase III randomized study of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab (herceptin) in women with node positive breast cancer that overexpresses HER2

Randomised phase II with run into phase III trial of SIR-spheres plus systemic chemotherapy versus systemic chemotherapy alone in patients with non-resectable liver metastases from primary adenocarcinoma of large bowel

Development of a dose calculation scheme for bolus 5-fluorouracil plus folinic acid using pretreatment dihydrouracil ratio

Hepatic metabolism and biliary excretion as deterinants of vinorelbine disposition. Relationships of vinorelbine toxicity to specific tests of liver function and to body surface area.

Phenoxodiol trial for metastatic cancer (prostate, lung, pancreatic and renal carcinomas and melanoma; and more recently leukemia)

Maintenance chemotherapy in hormone non-responsive breast cancer

Sentinal lymph node biopsy versus axillary clearance in operable breast cancer

Phase III randomised trial of paclitaxel and carboplatin versus triplet or sequential doublet combinations in patients with epithelial ovarian or primary peritoneal carcinoma

ZEST trial: a double-blind, placebo-controlled trial of Zoloft's effects on symptoms and survival in advanced cancer. Antidepressants, well-being and survival in advanced cancer.

Adjuvant chemotherapies in resectable pancreatic cancer

Twins: timing of birth at term

Phase III trial to evaluate oral chemotherapy with capecitabine versus standard chemotherapy with CMF for advanced breast cancer

Phase II study of induction therapy using Idarubicin and infusional high dose cytarabine for adult patients with de novo untreated acute lymphoblastic leukaemia

Adjuvant tamoxifen longer against shorter (ATLAS) clinical trial in early breast cancer

Phase II study of intravenous vinorelbine (Navelbine) and capecitabine (Xeloda) in patients with advanced breast cancer

Nonmyeloablative allogenic stem cell transplantation (NMSCT) in adults with intermediate and adverse prognosis AML in first complete remission

Phase III trial of primary therapy for B-cell chronic lymphocytic leukaemia

Randomised three-arm multicentre comparison of 1 year and 2 years of herceptin versus no herceptin in women with HER2-positive primary breast cancer who have completed adjuvant chemotherapy

Low dose cytotoxics as anti-angiogenesis treatment following adjuvant induction chemotherapy for patients with ER-Negative and PgR negative breast cancer

Phase III study of regional radiation therapy in early breast cancer.

Phase III limited institution pilot study of acute lymphoblastic leukaemia for the Australian & New Zealand Children's Haematology Oncology Group

Pre- and post-operative chemotherapy with oxaliplatin 5-fluorouracil-leucovorin versus surgery alone in resectable liver metastases from colorectal origin: phase III study

Randomised trial of preoperative radiotherapy for stage T3 adenocarcinoma of rectum

Phase III randomised double-blind placebo controlled study of rofecoxib (Vioxx) in colorectal cancer patients following potentially curative therapy

Phase II pilot study of Glivec (imatinib mesylate, formerly known as STI571) combined with inductions chemotherapy in blast phase chronic myeloid leukaemia and philadelphia-positive acute lymphoblastic leukaemia

Randomised trial of Idarubicin dose escalation in consolidation therapy following intensive induction chemotherapy incorporating high-dose cytarabine in patients with untreated adult acute myeloid leukaemia

Thoracic stabilisation study: a randomisation comparison of the effect of immobilisation: no immobilisation and immobilisation

Patients' perceptions of adjuvant chemotherapy for early colon cancer: what makes it worthwhile?

Randomised comparison of first line docetaxel/gemcitabine doublet chemotherapy versus sequential single agent chemotherapy (docetaxel followed by gemcitabine) in stage 111B/IV non-small-cell lung cancer

Randomised phase II study of two regimens of palliative chemoradiation therapy in the management of locally advanced non-small lung cancer

Prospective multicentre study of involved-field radiotherapy with transplantation for Hodgkin's disease and non-Hodgkin's disease lymphoma

Phase III adjuvant trials in pancreatic cancer comparing 1. 5-fluorouracil and D-L folinic acid versus 2. gemcitabine versus 3. no adjuvant treatment

Phase II study of a modified 'hyper CVAD' frontline therapy for patients with poor prognosis diffuse large B-cell and peripheral T-cell non-hodgkin's lymphoma

Randomised multicentre trial of involved field radiotherapy versus involved field radiotherapy plus chemotherapy for stage I-II low grade follicular lymphoma

Feasibility study to evaluate adjuvant chemoradiotherapy for gastric cancer

Prospective, non-randomised study of chemotherapy and radiotherapy for osteolymphoma (OL)

Randomised phase III study in advanced oesophageal cancer to compare quality of life and palliation of dysphagia in patients treated with radiotherapy versus chemo-radiotherapy.

Phase II study of idarubicin based combined modality therapy in primary central nervous system lymphoma

Multicentre phase III study comparing radical synchronous chemo-radiation vs radical radiation alone in the definitive management of muscle invasive TCC of the urinary bladder following maximal trans-urethral resection

Randomised study of ice plus rituximab (R-ICE) versus DHAP plus rituximab (R-DHAP) in previously treated patients with CD 20 positive diffuse large B-cell lymphoma, eligible for transplantation, followed by randomised maintenance treatment with rituxima

Immunotherapy of melanoma with dendritic cells vaccines

Molecular epidemiology of ovarian cancer: Australian Ovarian Cancer Study

Randomised double-blind trial of amifostine vs placebo for radiation-induced xerostomia in patients with head and neck cancer

Randomised clinical trial of surgery versus surgery plus adjuvant radiotherapy for regional control in patients with completely resected macroscopic nodal metastatic melanoma

Multicentre randomised phase III study of low-dose Thalidomide, prednisolone and zoledronic acid versus prednisolone and zoledronic acid for post ASCT maintenance therapy in patients with multiple myeloma

Multicentre randomised phase II study of the safety and efficiacy of thalidomide post-allogenic stem cell/bone marrow transplantation in multiple myeloma

Investigation of a new method for chemotherapy dose computation in cancer patients

Randomised trial investigating the effect on biomedical (PSA) control and survival of different durations of adjuvant androgen deprivation in association with definite radiation treatment for localised carcinoma of the prostate (RADAR)

Cancer pain education package for patients and carers: development and trial

Improving outcomes for people with cancer: consultation skills training with oncologists

Enhancing patient participation and understanding: a randomised controlled trial of a question prompt list for palliative care patients

Open-label, phase II trial to assess symptom control, weight change and the tolerabiliity of olanzapine in cancer patients with anorexia-cachexia syndrome.

Pilot study to determine the efficacy and safety of Glivec (ST1571) alone and Glivec (ST1571) plus intron A in the early recovery phase post autologous blood or marrow transplant for advanced phase chronic myeloid leukaemia and Ph-positive acute lymphoblastoma

Randomised trial of chlorambucil versus fludarabine as initial therapy of Waldenstrom's macroglobulinaemia and splenic lymphoma with villous lymphocytes

Phase II randomised study to assess the response of fludarabine in combination with cyclophosphamide (F-C) versus fludarabine in combination with cyclophosphamide and MabThera (F-C-M) in patients with untreated mantle cell lymphoma.

Clinicopathological study of Burkitt's and Burkitt-like non-Hodgkin's lymphoma

Phase II study of CHOP, with intrathecal methotrexate followed by radiotherapy in patients with primary testicular non-Hodgkin's lymphoma