Trials > Cardiovascular > VIGOUR > Recruitment

Recruitment to international VIGOUR trials

Trial	Regional recruitment	World recruitment	CTC contribution	Publication of results
GUSTO-I compared four thrombolytic treatments in reducing mortality after myocardial infarction	2 287	41 021	Australian coordinating centre	New England Journal of Medicine 1993; 329: 673-682
GUSTO-II acompared hirudin with heparin in acute coronary syndromes	1264	12 500	Australian coordinating centre	New England Journal of Medicine 1993; 329: 673-682
GUSTO-IIb compared hirudin with heparin in acute coronary syndromes	1001	12 142	Australian coordinating centre	New England Journal of Medicine 1996 335: 775-782
PARAGON-A compared of lamifiban + heparin with lamifiban alone in acute coronary syndromes	424	2282	Australian and New Zealand data coordinating centre	Circulation 1998; 97: 2386-2395
PARAGON-B compared lamifiban with placebo (both with aspirin and heparin) in acute coronary syndromes	494	7225	Asia-Pacific coordinating centre	Circulation 2002; 105: 316-321
SYMPHONY compared two doses of sibrafiban with aspirin in acute coronary syndromes	765	9243	Asia-Pacific coordinating centre	Lancet 2000; 355: 337-345
2nd SYMPHONY compared high-dose or low-dose sibrafiban + aspirin with aspirin alone in acute coronary syndromes	433	6637	Asia-Pacific coordinating centre	Circulation 2001; 103: 1727-1733
HERO-2 compared bivalirudin + streptokinase with heparin + streptokinase in myocardial infarction	1752	17 073	Asia-Pacific data coordinating centre and international statistical centre	Lancet 2001; 358: 1855-1863.