NHMRC Clinical Trials Centre: breast cancer

NHMRC Clinical Trials Centre

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Breast cancer trials

SNAC2: a randomised trial of sentinel node based management versus axillary clearance in operable breast cancer	Sentinel node biopsy versus axillary clearance: the SNAC trial
Cooperative group: Royal Australasian College of Surgeons Participants Women with operable breast cancer in whom lymph-node staging is indicated. Main difference from the SNAC1 trial: women with larger and multiple breast tumours are eligible Outcome measures . locoregional recurrence (primary) . distant recurrence . survival Recruitment target: 1012 (Australia and New Zealand) Status: Open to recruitment Funding: NHMRC, state cancer councils, New Zealand Cancer Society grants	Cooperative group: Royal Australasian College of Surgeons Participants Women with operable breast cancer in whom lymph-node staging is indicated Outcome measures • early axillary morbidity • arm swelling • axillary tumour recurrence • survival • disease-free survival • use of adjuvant therapies • number of surgical episodes • days in hospital Recruitment: 1088 Status: Closed to recruitment. Funding: Medical Benefits Fund, NHMRC

The CTC is statistical centre for the Australian New Zealand Breast Cancer Trials Group.