PERINATAL TRIALS REPORT

PT0547

Prediction of normal vaginal delivery

Plain Language Summary:     We have developed an antenatal test predicting the likelihood of normal vaginal delivery in low-risk nulliparous women at 36-38 weeks gestation. This test has a R2=0.33 and a discriminative ability c=0.85. With the help of the STEP unit (Prof.Les Irwig) at Usyd we intend to test the model in a pilot multicentre RCT. Women with a poor test result (<= 20th centile) are randomized to disclosure/nondisclosure. Disclosure involves handing over of a decision aid offering elective caesarean section at 39 weeks gestation. Women will be followed up at 3 months and 2 years after childbirth.

Trial status:                         Open to accrual

Date trial opened to accrual:    May 2005

Expected accrual period:         24 months

Trial Objective:

Randomized controlled trial of the effect of test disclosure of a novel antenatal test determining the likelihood of normal vaginal delivery.

Type of administration:        Multi-centre national

Prinicipal Investigator/s:     Hans Peter Dietz

                                        Ph 61 2 47341809

                                        Email hpdietz@bigpond.com

© IMPACT/PSANZ 2001