PERINATAL TRIALS REPORT

PT0545

A comparison of Propofol and Suxamethonium as induction agents for neonatal endotracheal intubation

Plain Language Summary:     The aim is to compare the effectiveness of Propofol as an induction agent with current regimen of Morphine/Atropine/Suxamethonium for semi-elective intubation. This was a non blinded randomised controlled trial with each infant designated to induction with either of the drugs after informed parental consent, and the outcomes so far have been encouraging as we found that Propofol was a good alternative to Morphine/Atropine/Suxamethonium regimen.

Trial status:                         Open to accrual

Date trial opened to accrual:    March 2004

Expected accrual period:   2 years or to 60 patients, whichever comes first     

Trial Objective:

To compare the effectiveness of propofol as an induction agent with regimen of morphine, Atropine and Suxamethonium for neonatal intubation.

Type of administration:        Single centre

Prinicipal Investigator/s:     

Dr Julee Oei

Ph (02) 9382 6151

Email oeij@sesahs.nsw.gov.au

Dr Satish Babu Ghanta

Ph (02) 9382 6170

Email satishbabughanta@sesahs.nsw.gov.au

Contact Person/s:             

Dr Julee Oei

As above

© IMPACT/PSANZ 2001