PERINATAL TRIALS REPORT

PT0426

ACTOTTAB

Twins: Timing of birth at Term

Plain Language Summary:      The aims of this trial is to assess whether a policy of elective birth at 37 weeks gestation compared with a policy of expectant management in women with a twin pregnancy affects the risks of perinatal death and the risk of serious complications for the infant. When allocated to the Elective Delivery Group will undergo elective birth from 37 weeks gestation either by induction of labour or caesarean section (as assessed by the women and her obstetrician). Women allocated to the Expectant Management Group will await the spontaneous onset of labour where there is a plan for vaginal birth. Where caesarean section is preferred mode of birth, this will be conducted from 39 weeks.

Trial status:                       Opened to accrual

Date trial open to accrual:   March 2003

Expected accrual period: 3 years

Trial Objective:                   

The specific aims of this trial are to assess whether a policy of elective birth at 37 weeks gestation compared with a policy of expectant management in women with a twin pregnancy affects

1. the risk of perinatal death (still birth or neonatal death); and

2. the risk of serious complications for the infant

Type of administration:        Multi-centre international

Principal Investigator/s:       Professor Jeffery Robinson

                                         Ph 61 8 8161 7619

                                         Email jeffrey.robinson@adelaide.edu.au

                                         Associate Professor Caroline Crowther

                                         Ph 61 8 8161 7647

                                         Email caroline.crowther@adelaide.edu.au

Contact Person/s:               Dr Jodie Dodd

                                         Ph 61 8 8161 7652

                                         Email jodie.dodd@adelaide.edu.au

© IMPACT/PSANZ 2001